Recombinant Human IL-17 （IL-17A）5ug（PeproTech） 編號：200-17

貨號：200-17
規格：5ug
產地：PeproTech
Biological Activity: Assay #1: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximay 2 ng/ml. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family. 
Cross Reactivity: Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.  IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains. Mouse 
Description: Synonyms: IL-17,CTLA-8. The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Country of Origin: USA

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